![]() ![]() In plant metabolomics, NMR-based strategies are considered a golden method providing both a holistic view of the chemical profiles and a correlation between the metabolome and bioactivity, becoming a corner stone of drug development from natural products. Fluctuations in sucrose concentrations occurred at every sampling date, however, sucrose dynamics in the bridge-grafted trees appeared to be restored after one year.The increase in multidrug resistance and lack of efficacy in malaria therapy has propelled the urgent discovery of new antiplasmodial drugs, reviving the screening of secondary metabolites from traditional medicine. A total of 300 bark samples were collected bi-monthly over a 12-month period to perform targeted 1H NMR based metabolomic analyses to determine the sucrose concentration of each sample. dentata trees using the technique of bridge-grafting. This study investigated whether the flow of sucrose can be restored in girdled O. ![]() The removal of bark from a tree affects its foliage, flowering, fruiting, seeding, basal sprouting and rooting since the removal of phloem tissue during girdling affects both the basipetal flow of carbohydrates from the canopy of the tree to the root system and the acropetal flow of amino acids, sugars and hormones from the roots to the canopy. Due to uncontrolled harvesting of bark by informal commercial harvesters, these trees are often found girdled in natural areas. Curtisia dentata bark is further applied as an aphrodisiac, and to “purify the blood”. dentata is taken for stomach ailments, diarrhea and sexually transmitted diseases. bullata is used for headaches, as an emetic for both nervous and urinary disorders, and for diarrhea, whereas the bark of C. (Curtisiaceae) are two South African indigenous medicinal tree species of which the bark is overexploited due to its high demand in the local medicinal plant trade. (Lauraceae) and Curtisia dentata (Burm.f.) C.A.Sm. ![]()
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